Case Report


Fulminant hepatitis A in a robust adult: a case report of acute liver failure requiring urgent living donor liver transplantation

Hussein Zaghloul Kandeel, Mohamad Abdelmonem Omar, Hesham Fawzy Kewan, Mahmod Elshahat Makhlof, Anand Bhaskarrao Kotgire, Mohamed Aly Elbouhy, Rami Khaled Abou El Foul, Syed Urooj Ahmed

Abstract

Hepatitis A virus (HAV) infection is generally a self‑limited disease; however, in adults it can rarely progress to acute liver failure (ALF), a rapidly evolving and potentially fatal condition. Although HAV‑related ALF occurs in <1% of the general adult population, the incidence may rise to about 10% in hospitalized or severe cases, with reported outcomes of 55% recovered, 31% transplanted, and 14% died. Early recognition, rapid prognostic assessment, and timely referral to a transplant center are essential because deterioration can occur abruptly and unpredictably.

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